clinical

Jul 28, 2026

Intratumor Heterogeneity

Jul 28, 2026

Therapy Resistance

clinical

Jul 28, 2026

Jones, J. R., Weinhold, N., Ashby, C., Walker, B. A., Wardell, C., Pawlyn, C., Rasche, L., Melchor, L., Cairns, D. A., Gregory, W. M., Johnson, D., Begum, D. B., Ellis, S., Sherborne, A. L., Cook, G., Kaiser, M. F., Drayson, M. T., Owen, R. G., Jackson, G. H., Davies, F. E., Greaves, M., & Morgan, G. J. (2019). Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients. Haematologica, 104(7), 1440–1450.

Jul 16, 2026

Jamal-Hanjani, M., Wilson, G. A., McGranahan, N., et al. (2017). Tracking the evolution of non–small-cell lung cancer. New England Journal of Medicine, 376(22), 2109–2121.

Jul 11, 2026

Immune Evasion

Jul 11, 2026

Neoantigen

Jul 11, 2026

Chavarriaga (2025) — ASCO GU 2025: Evolution of ctDNA Detection with Next Generation Technology

Jul 11, 2026

Life in the Lab Staff. (2025, January 23). Cell-Free DNA (cfDNA) vs. Circulating Tumor DNA (ctDNA) Explained. Life in the Lab Blog. Thermo Fisher Scientific.

Jul 11, 2026

Gerlinger, Rowan, Horswell, et al. (2012) — Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Jul 05, 2026

Abbosh et al. (2017) — Phylogenetic ctDNA Analysis Depicts Early-Stage Lung Cancer Evolution

Jul 05, 2026

Khatami & Tavangar (2018) — Circulating Tumor DNA (ctDNA) in the Era of Personalized Cancer Therapy

Jul 05, 2026

Lee, Kim, Nam, et al. (2026) — Clonal Evolution and Mutational Trajectories of Metastatic Colorectal Cancer Shaped by Anticancer Therapies

Jul 05, 2026

Miething (2019) — Clonal Evolution in Multiple Myeloma

Jul 05, 2026

Mikutenaite, Karadoulama, Favero, et al. (2025) — Clonal Evolution and Transcriptional Plasticity Shape Metastatic Dissemination Routes in Prostate Cancer

Jul 05, 2026

Spina, Bruscaggin, Cuccaro, et al. (2018) — Circulating Tumor DNA Reveals Genetics, Clonal Evolution, and Residual Disease in Classical Hodgkin Lymphoma

Jul 05, 2026

Stejskal, Goodarzi, Srovnal, Hajdúch, van 't Veer, & Magbanua (2023) — Circulating Tumor Nucleic Acids: Biology, Release Mechanisms, and Clinical Relevance

Jul 05, 2026

Walens, Lin, Damrauer, et al. (2020) — Adaptation and Selection Shape Clonal Evolution of Tumors During Residual Disease and Recurrence

Jul 05, 2026

Wander, Weipert, Cabel, et al. (2026) — Real-World Cell-Free ctDNA Analysis Identifies CDK4/6 Inhibitor Resistance and Tumor Evolution in HR+ Advanced Breast Cancer

Jul 05, 2026

Weng, Cain, Comben, et al. (2026) — Recurrent Intra-tumour Heterogeneity is a Hallmark of Metastatic Prostate Cancer

Jul 03, 2026

McDermott, Gao, & Murphy (2015) — Chromothriptic Cure of WHIM Syndrome: Implications for Bone Marrow Transplantation

Jun 20, 2026

Metastasis

clinical

Jun 20, 2026

Al Bakir et al. (2023) — The Evolution of NSCLC Metastases in TRACERx

Jun 20, 2026

Clonal Evolution

Explorer

clinical

Intratumor Heterogeneity

Therapy Resistance

Jamal-Hanjani, M., Wilson, G. A., McGranahan, N., et al. (2017). Tracking the evolution of non–small-cell lung cancer. New England Journal of Medicine, 376(22), 2109–2121.

Immune Evasion

Neoantigen

Chavarriaga (2025) — ASCO GU 2025: Evolution of ctDNA Detection with Next Generation Technology

Life in the Lab Staff. (2025, January 23). Cell-Free DNA (cfDNA) vs. Circulating Tumor DNA (ctDNA) Explained. Life in the Lab Blog. Thermo Fisher Scientific.

Gerlinger, Rowan, Horswell, et al. (2012) — Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Abbosh et al. (2017) — Phylogenetic ctDNA Analysis Depicts Early-Stage Lung Cancer Evolution

Khatami & Tavangar (2018) — Circulating Tumor DNA (ctDNA) in the Era of Personalized Cancer Therapy

Lee, Kim, Nam, et al. (2026) — Clonal Evolution and Mutational Trajectories of Metastatic Colorectal Cancer Shaped by Anticancer Therapies

Miething (2019) — Clonal Evolution in Multiple Myeloma

Mikutenaite, Karadoulama, Favero, et al. (2025) — Clonal Evolution and Transcriptional Plasticity Shape Metastatic Dissemination Routes in Prostate Cancer

Spina, Bruscaggin, Cuccaro, et al. (2018) — Circulating Tumor DNA Reveals Genetics, Clonal Evolution, and Residual Disease in Classical Hodgkin Lymphoma

Stejskal, Goodarzi, Srovnal, Hajdúch, van 't Veer, & Magbanua (2023) — Circulating Tumor Nucleic Acids: Biology, Release Mechanisms, and Clinical Relevance

Walens, Lin, Damrauer, et al. (2020) — Adaptation and Selection Shape Clonal Evolution of Tumors During Residual Disease and Recurrence

Wander, Weipert, Cabel, et al. (2026) — Real-World Cell-Free ctDNA Analysis Identifies CDK4/6 Inhibitor Resistance and Tumor Evolution in HR+ Advanced Breast Cancer

Weng, Cain, Comben, et al. (2026) — Recurrent Intra-tumour Heterogeneity is a Hallmark of Metastatic Prostate Cancer

McDermott, Gao, & Murphy (2015) — Chromothriptic Cure of WHIM Syndrome: Implications for Bone Marrow Transplantation

Metastasis

Al Bakir et al. (2023) — The Evolution of NSCLC Metastases in TRACERx

Bozic et al. (2013) — Evolutionary Dynamics of Cancer in Response to Targeted Combination Therapy